{"id":500,"date":"2024-10-07T16:13:08","date_gmt":"2024-10-07T16:13:08","guid":{"rendered":"https:\/\/www.tepedesign.cz\/?page_id=500"},"modified":"2024-10-17T20:07:45","modified_gmt":"2024-10-17T20:07:45","slug":"preeklampsie","status":"publish","type":"page","link":"https:\/\/www.znojmo-prenatal.cz\/index.php\/preeklampsie\/","title":{"rendered":"Preeklampsie"},"content":{"rendered":"\t\t
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Preeklampsie<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Z\u00e1va\u017en\u00e9 hypertenzn\u00ed onemocn\u011bn\u00ed v t\u011bhotenstv\u00ed, kter\u00e9 postihuje 4-8% t\u011bhotn\u00fdch \u017een.<\/span><\/h5>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Co je preeklampsie?<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Preeklampsie (PE)\u00a0je definov\u00e1na jako nov\u00fd v\u00fdskyt hypertenze (>140\/90mmHg), nebo proteinurie (\u2265 0,3 g \/ 24 h) po 20.t\u00fddnu t\u011bhotenstv\u00ed<\/span><\/strong><\/h5>
PE je zp\u016fsobena dysbalanc\u00ed placent\u00e1rn\u00edch angiogenn\u00edch a antiangiogenn\u00edch faktor\u016f. Riziko PE lze stanovit ji\u017e p\u0159i screeningu v 1. trimestru.<\/span><\/strong><\/h5>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Kter\u00e9 t\u011bhotn\u00e9 maj\u00ed zv\u00fd\u0161en\u00e9 riziko preeklampsie?<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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  • \u00a0preeklampsie v osobn\u00ed nebo rodinn\u00e9 anamn\u00e9ze<\/span><\/li>
  • \u00a0prvn\u00ed t\u011bhotenstv\u00ed<\/span><\/li>
  • \u00a0v\u011bk pod 18 let nebo nad 30 let<\/span><\/li>
  • \u00a0obezita<\/span><\/li>
  • \u00a0oplodn\u011bn\u00ed pomoc\u00ed asistovan\u00e9 reprodukce (IVF)<\/span><\/li>
  • \u00a0v\u00edce\u010detn\u00e9 t\u011bhotenstv\u00ed<\/span><\/li>
  • \u00a0t\u011bhotensk\u00fd diabetes<\/span><\/li>
  • \u00a0avitamin\u00f3za<\/span><\/li>
  • \u00a0n\u011bkter\u00e1 onemocn\u011bn\u00ed p\u0159ed t\u011bhotenstv\u00edm \u2013 hypertenze, diabetes, migr\u00e9ny, revmatoidn\u00ed artritida, onemocn\u011bn\u00ed ledvin<\/span><\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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    Nejz\u00e1va\u017en\u011bj\u0161\u00ed n\u00e1sledky PE pro matku:<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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    • eklampsie, HELLP syndrom, plicn\u00ed ed\u00e9m<\/span><\/li>
    • vysok\u00e9 riziko kardiovaskul\u00e1rn\u00edch nemoc\u00ed chronick\u00e1 hypertense, c\u00e9vn\u00ed mozkov\u00e1 p\u0159\u00edhoda, po\u0161kozen\u00ed ledvin<\/span><\/li>
    • \u017eeny s PE v anamn\u00e9ze maj\u00ed 2-n\u00e1sobn\u00e9 riziko \u00famrt\u00ed na c\u00e9vn\u00ed mozkovou p\u0159\u00edhodu ve srovn\u00e1n\u00ed se \u017eenami bez PE<\/span><\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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      Nejz\u00e1va\u017en\u011bj\u0161\u00ed n\u00e1sledky PE pro plod:<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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      • p\u0159ed\u010dasn\u00fd porod<\/span><\/li>
      • n\u00edzk\u00e1 porodn\u00ed hmotnost<\/span><\/li>
      • syndrom respira\u010dn\u00ed t\u00edsn\u011b<\/span><\/li>
      • \u00a0komplikace p\u0159ed\u010dasn\u00e9ho porodu (mozkov\u00e1 obrna, poruchy zraku, slepota)<\/span><\/li>
      • zv\u00fd\u0161en\u00e9 riziko v dosp\u011blosti: CMP, ICHS, metabolick\u00fd syndrom<\/span><\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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        Sou\u010dasn\u00fd diagnostick\u00fd \u201czlat\u00fd standard\u201d<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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        V sou\u010dasnosti je k diagnose PE pou\u017e\u00edv\u00e1no m\u011b\u0159en\u00ed krevn\u00edho tlaku a stanoven\u00ed proteinurie. Tato vy\u0161et\u0159en\u00ed maj\u00ed n\u00edzkou senzitivitu a specifi\u010dnost \u2013 positivn\u00ed prediktivn\u00ed hodnota je 20%.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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        Dysbalance angiogenn\u00edch faktor\u016f<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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        V sou\u010dasn\u00e9 dob\u011b je metodou volby k diagnose PE stanoven\u00ed dysbalance angiogenn\u00edch faktor\u016f. Tuto je mo\u017en\u00e9 zjistit ji\u017e\u00a0p\u0159ed v\u00fdskytem klinick\u00fdch\u00a0<\/em><\/strong>p\u0159\u00edznak\u016f\u00a0<\/em><\/strong>PE<\/em><\/strong>.<\/em><\/span><\/p>

        V r\u00e1mci prvotrimestr\u00e1ln\u00edho screeningu Downova<\/strong>\u00a0syndromu\u00a0<\/strong>stanovujeme u \u017een PLGF. Tento parametr je pak zahrnut do algoritmu v\u00fdpo\u010dtu rizika posti\u017een\u00ed plodu Downov\u00fdm syndromem a z\u00e1rove\u0148 je hodnotic\u00edm softwarem stanoveno riziko rozvoje preeklampsie, p\u0159\u00edpadn\u011b r\u016fstov\u00e9 retardace plodu.<\/span><\/p>

        Do v\u00fdpo\u010dtu je zahrnut i pr\u016fm\u011brn\u00fd arteri\u00e1ln\u00ed tlak a pr\u016ftok krve v uterinn\u00edch arteri\u00edch.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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        Jak\u00e9 jsou mo\u017enosti l\u00e9\u010dby, pokud je zji\u0161t\u011bno vysok\u00e9 riziko PE?<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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        P\u0159i positivn\u00edm screeningu PE v 1. trimestru t\u011bhotenstv\u00ed v\u010dasn\u00e1 aplikace 150 mg aspirinu denn\u011b sn\u00ed\u017e\u00ed v\u00fdskyt \u010dasn\u00e9 PE o\u00a090%!!!<\/strong><\/span><\/p>

        Akolekar R. Competing risks model in early screening for<\/em><\/span><\/p>

        preeclampsia by biophysical and biochemical markers. Fetal<\/em><\/span><\/p>

        Diag Ther 2013;33(1):8-15<\/em>.<\/em><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

        Preeklampsie Z\u00e1va\u017en\u00e9 hypertenzn\u00ed onemocn\u011bn\u00ed v t\u011bhotenstv\u00ed, kter\u00e9 postihuje 4-8% t\u011bhotn\u00fdch \u017een. Co je preeklampsie? Preeklampsie (PE)\u00a0je definov\u00e1na jako nov\u00fd v\u00fdskyt […]<\/p>\n","protected":false},"author":4,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"","ast-site-content-layout":"full-width-container","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-500","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.znojmo-prenatal.cz\/index.php\/wp-json\/wp\/v2\/pages\/500","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.znojmo-prenatal.cz\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.znojmo-prenatal.cz\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.znojmo-prenatal.cz\/index.php\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.znojmo-prenatal.cz\/index.php\/wp-json\/wp\/v2\/comments?post=500"}],"version-history":[{"count":19,"href":"https:\/\/www.znojmo-prenatal.cz\/index.php\/wp-json\/wp\/v2\/pages\/500\/revisions"}],"predecessor-version":[{"id":1356,"href":"https:\/\/www.znojmo-prenatal.cz\/index.php\/wp-json\/wp\/v2\/pages\/500\/revisions\/1356"}],"wp:attachment":[{"href":"https:\/\/www.znojmo-prenatal.cz\/index.php\/wp-json\/wp\/v2\/media?parent=500"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}